Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products 87 Matrix-Trilogie

Matrix-Trilogie

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3Methodisches Vorgehen17

Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products 87 Matrix-TrilogieMore than ten years have elapsed since the publication of a compre hensive review on the quassinoids, the bitter principles of the Simaroubaceae family (80). Interest in these terpenoids has increased enormously in recent years due in part to the finding of the American National Cancer Institute in the early 1970s that these compounds display marked antileukemic activity. Furthermore, a wide spectrum of other biological properties for the quassinoids